The debate rages on between “wakefulness drugs” designed to treat narcolepsy, sleep apnea and shift work sleep disorders that also happen to assist people who need an extra boost of mental clarity so they can enjoy peak performance at school or at work.
If you’re trying to decide, these facts may help, but to assess the true benefits of either, it’s always a good idea to try them both to see how your body responds.
What is Modafinil?
According to the National Institutes of Health, “Modafinil is a waking drug prescribed to narcolepsy patients, but its usage among healthy individuals is increasing to enhance their alertness or to mitigate fatigue.”
Scientists still haven’t figured out why it works its magic.
What is Armodafinil?
This drug is prescribed for patients dealing with “excessive sleepiness.”
It “is a single-isomer of modafinil,” and while its action mechanism remains unknown, it is classified as an eugeroic, providing long-lasting mental arousal and treating obstructive sleep apnea, narcolepsy and shift work sleep disorder (SWSD).
The history behind Modafinil and Armodafinil
Modafinil, frequently sold under the brand name Provigil, was developed in France by neurophysiologist Michel Jouvet at Lafon Laboratories in the late 1970s.
It was first prescribed in France in 1986 exclusively for narcolepsy sufferers. Approved by the U.S. Food and Drug Administration (FDA) in 1998, doctors also prescribe this drug to shift work disorder and sleep apnea sufferers.
In 2003, the pharma company Teva began to make the drug in the U.S.
Armodafinil (brand name Nuvigil), received FDA approval on June 18, 2007. Produced by Cephalon, the formulation can successfully treat obstructive sleep apnea/hypopnea syndrome (OSAHS), narcolepsy and shift work sleep disorder (SWSD).
The patent for Nuvigil expires in 2023, at which point, competitor products are likely to appear on the market.
The science behind Modafinil and Armodafinil
Like most chemical compounds, the science comes down to the structure of molecules and if you need a simplistic way of understanding of how these two formulations differ, think about fraternal twins.
They may look so much alike, you conclude, that they’re identical, but in fact, they are anything but.
Modafinil is classified as a racemic compound while Armodafinil contains only part of the molecular structure so it belongs in the enantiopure family.
Ask your friendly college chemistry teacher to go into more detail if you are interested in learning more.
Key differences between the Modafinil vs Armodafinil
-It’s harder to fall asleep after taking Modafinil.
-Modafinil appears to be more effective for keeping one awake for extended periods of time.
-You may not get the high Modafinil tends to trigger if you take Armodafinil.
-Consumers reporting stomach issues from taking Modafinil may tolerate Armodafinil better.
-A 200mg dose of Modafinil gives users the same clarity of thought as a 150 mg Armodafinil dose.
-Some say Armodafinil is a purer drug than Modafinil.
-Neither drug appear to be habit-forming, but if you are easily addicted, Armodafinil may be a better bet.
-Savvy consumers say they try both in order to judge which works best for their unique physiological makeups.
Subjective experiences reported by users of Modafinil vs Armodafinil
– “In my opinion, Modalert 200 is the premier form of Modafinil”
– “All versions of Modafinil are potent, pure and powerful.”
-“If money is no object, I’d start with 200 mg of Modalert.”
-“I consider Modvigil to be the most exceptional smart drug on the market, beating out Modalert.”
-“Modalert lasts more than 12 hours but Modvigil, a less potent drug, is likely to last me only 10 or 11.”
-“Modvigil definitely fits my budge, while Modalert 200 doesn’t.”
The most popular brands of Modafinil and Armodafinil
Armodafinil: Waklert and Artvigil
Modafinil: Modalert 200; Modvigil; Modafil MD
Modalert vs Modvigil
-Modafinil has been on the market longer than Modvigil so it may be easier to find.
-The chemical composition of both are so similar, it would take a chemist to differentiate them.
-The Modafinil patent has expired, which is why there are more generics on the market.
-The biggest difference between the two comes down to packaging, say some consumers.
Waklert vs Artvigil
-Waklert appears to be more popular than Artvigil, based on consumer reviews.
-Artvigil is cheaper than Waklert, so if money is your prime concern, this could make your decision.
-Based on testing, Waklert gets better reviews than Artvigil.
-If money is no object, people in the know recommend Waklert.
Why pick one over the other?
-Because your body tolerates it better and you suffer fewer side effects.
-Should you experience the same level of potency, availability is a deciding factor.
-Scuttle formulations that come with so many side effects, it’s not worth getting a smart boost.
-Pick the one with the fewest reports of addiction if you tend to become easily dependent upon drugs.
-Don’t take the one your friend recommends just because it works for him.
-Judge the effectiveness of the two and always choose the one that ups your performance while allowing you to get adequate sleep.